After Failed IVF


#1

I am sorry if you are going through a failed IVF cycle. I went through 5 of them before finally having our miracle baby.

I just wrote an article including suggestions on what to do after you go through a failed IVF. Just thought some of you might want to check it out. (link is in sig)

Don’t give up, it is all worth it in the end!


#2

The drugs used for ovarian stimulation have mild side effects for some women, including mild bruising and soreness at the injection site, headaches, an upset stomach, and mood swings. Another side effect is ovarian hyperstimulation syndrome (OHSS.) This happens when the ovaries produce many follicles and fluid may leak from the blood vessels into the abdominal cavity and lungs. Usually this is mild and resolves on its own without treatment. In severe cases OHSS can result in very enlarged ovaries, dehydration, and large amounts of fluid in the lungs and abdomen. In less than one percent of women undergoing egg retrieval through IVF, OHSS can lead to blood clots and kidney failure, according to ASRM. This is one of the reasons that patients who are taking gonadotropins go for frequent monitoring, to make sure this is not starting to happen. If you do have a high-multiple pregnancy, defined as three or more fetuses, it is strongly suggested that you consult a physician who specializes in high-risk pregnancies, or you may want to consider reducing the number of embryos you are carrying. Both possibilities should be discussed with the doctor and your partner if you have one. Fertility doctors can moderate the amount of drugs being prescribed or alter the medication regimen if they see any indication of potential trouble. So make sure you check on this next time. Like mine in Bio tex.


#3

Our nurse at bio tex com has told us a plenty of useful & interesting things concerning pregnancy and delivery. Here’s what I got to know about the amniotic fluid which is the clear, slightly yellowish fluid within the amniotic sac that surrounds the baby in the uterus. The baby grows in this amniotic sac, surrounded by the amniotic fluid, as he learns to move his limbs, open his eyes and breathe. Amniotic fluid levels generally sit at approximately 800ml through most of the pregnancy, dropping slightly in most cases to about 600ml by the time a woman reaches the 40 week mark. The amniotic fluid has many purposes. It helps to cushion hard blows and jolts to your belly to protect the baby and it allows your baby the freedom to move while permitting symmetrical musculoskeletal development. It also maintains an even temperature so that your baby does not get too hot or too cold, even if you are extremely hot or cold. Amniotic fluid also helps your baby develop his lungs.
Thank you for the link offered. It’s awesome you took time to share all those things with others. My positive thoughts going your way.


#4

I believe if one faces multiple ivf failures then one should seek help through PGS and PGD testing. which can be performed on both fresh and frozen/thawed embryos, can identify genetically viable embryos for implantation. Any flaw in the genetic makeup of an embryo is a major cause of implantation failure. This also eliminates the prospect of a child being born with a birth defect or a genetic mutation predisposing the child to health problems. PGD screens for one specific genetic defect. It is often performed when one (or both) of the parents is known to have. or is suspected of having, a particular genetic defect that may be present in their family history. Preimplantation genetic screening (PGS) tests for many possible genetic defects (Such as Down syndrome, cystic fibrosis and the BRCA genetic mutations that predispose a mother and her children to ovarian and breast cancers.)
Anyway, thank you for sharing your ideas. Sometimes not even a dr can tell you why the iVF cycle failed. But if sth makes you suspicious, then it’s always better to take the benefits from the offered testings. I’m praying for less women going throught the failures. May the most of the ivf attempts bring people luck. Blessings.


#5

I’m with you. Quite a good option to make sure the embies are more likely to be healthy. PGD is is done on day-3 embryos which have 4-8 cells. A small cell or blastomere is removed from each embryo and is tested for the genetic abnormality. The risk of damaging the embryo at this point is very low. Only embryos that show normal results are transferred back to the uterus. Studies have shown there is no increased risk of birth defects following PGD. It is important to remember that: PGD is not 100% accurate because only one cell is tested. The technique is technically challenging and requires great expertise. Therefore, an amniocentesis or chorionic villus sampling is suggested after a pregnancy is documented. PGD testing ranges from approximately $2k to $5k and is not covered by most insurance companies. Not all IVF centers do PGD. The experimental techniques require great expertise and should only be done by qualified personnel. It is preferable if the lab performing PGD has a PhD or MD trained medical geneticist responsible for the PGD laboratory.


#6

If you are considering doing PGD, make certain the laboratory is experienced, does a large number of
cases, and is certified. Ask your doctor at the IVF clinic or the lab director the following questions:
What training has the PGD laboratory personnel who are performing the testing have?
How long have they been doing the procedure?
When will you get the results of the PGD?
What will happen if all the embryos are genetically abnormal?
What the clinic’s success rate is for frozen embryo transfer following embryo biopsy?