[quote=musicgal]Ghost- question for you…I have one frozen already hatching blast. Unfortunately it is only a grade C but the RE said that the fact that it is hatching makes it a promising embryo. My husband and I are moving out of state from the clinic where our frozen embryo is and we would like to have it shipped to our new clinic. A nurse at the new clinic told us that success rates were lower with shipped/transported embryos. Do you know anything about this???
Thanks in advance[/quote]
Hatching is a good sign, but a low grade is still a factor. Hatching will not improve an ICM, for example. Also, check with your [I]prior[/I] clinic about whether their success rates are any better or worse with FET of hatching blasts. Some freezing protocols work best for moderate-sized blasts, not so well for hatching blasts.
I know that sometimes the embryos we’ve received were dead on arrival, but that is rare. A clinic would have lower success rates with shipped embryos for a few reasons. First, in rare cases they are harmed in shipping, although this would be a complete loss, and probably left out of any rate calculations (which are usually per transfer). It’s also possible that the clinic you spoke to is better at freezing than most, so FET with their own would have better success than FET with others. Another possibility is that their thaw/warming protocols are optimized for only their freezing/vitrification protocols, and not a good match for embryos frozen at other clinics. Perhaps all of these are at work to some extent.