BFN again, what treatment next?


#1

Hello ladies, I have that terrible feeling that I will be facing yet another “BFN”, see my signature. So, I am torn what to do next. I do have insurance so incredibly, a 2nd IVF is an option. Although like so many of you, my deepest greatest wish is to just have a plain-old natural pregnancy.
Ok, I am starting this thread in this forum and in one of the IVF forums as I want to see some replies. I really hope it helps me, as well as some others!!!

For the first IVF, my RE said I responded to the Long Lupron protocol well. They got 18 eggs, 16 matured in the lab, 10 fertilized with ISCI (this RE always does ICSI with all IVF’s), but then 8 of those 10 embryos “arrested” development (stopped growing and died I guess) and we were left with only 2 that were so “slow-growing” that we had to cancel our day 4 ET and transfer on day 5. On day 5, RE said that only 1 of them was slightly promising. We put both back in, and I got the BFN 2 weeks later. So, here’s what my RE advised to do next: I could either A) do inexpensive treatements and hope for the best, B) do the same IVF protocol again because I responded very well, but use donor sperm for a 1/2 of the eggs and see what happens. If my embryos thrive with some 20 year old guy’s sperm then we know it’s a sperm issue. If they are slow-growing again, then we know it’s a egg issue and we should move on to donor eggs. C) Do a 2nd IVF but use FSH only because a small % of women with PCOS are LH-dependent and this might be the answer.

So!

Any votes on what I should do next? :slight_smile:


#2

[quote=IMSPECIAL]Hello ladies, I have that terrible feeling that I will be facing yet another “BFN”, see my signature. So, I am torn what to do next. I do have insurance so incredibly, a 2nd IVF is an option. Although like so many of you, my deepest greatest wish is to just have a plain-old natural pregnancy.
Ok, I am starting this thread in this forum and in one of the IVF forums as I want to see some replies. I really hope it helps me, as well as some others!!!

For the first IVF, my RE said I responded to the Long Lupron protocol well. They got 18 eggs, 16 matured in the lab, 10 fertilized with ISCI (this RE always does ICSI with all IVF’s), but then 8 of those 10 embryos “arrested” development (stopped growing and died I guess) and we were left with only 2 that were so “slow-growing” that we had to cancel our day 4 ET and transfer on day 5. On day 5, RE said that only 1 of them was slightly promising. We put both back in, and I got the BFN 2 weeks later. So, here’s what my RE advised to do next: I could either A) do inexpensive treatements and hope for the best, B) do the same IVF protocol again because I responded very well, but use donor sperm for a 1/2 of the eggs and see what happens. If my embryos thrive with some 20 year old guy’s sperm then we know it’s a sperm issue. If they are slow-growing again, then we know it’s a egg issue and we should move on to donor eggs. C) Do a 2nd IVF but use FSH only because a small % of women with PCOS are LH-dependent and this might be the answer.

So!

Any votes on what I should do next? :)[/quote]

Thats a tough one! I would say that there is probably no point in doing the Femara and IUI’s again seeing as you did quite a few of them and didn’t have any luck (did you have ultrasounds with those? Did you make any eggs that matured?). honestly, I think you are going to be wasting your time with that. If your insurance DIDNT cover IVF, I would say go for it…but since it does, I don’t see the need to bother.

Now, as for the protocol, I say try and use the same one you did last time. You did make eggs, and there were enough of them, so why fix what isn’t broken?! To use a donor sperm though is a decision you and your husband are going to have to make. Is he ok with it? Has he had a complete SA done to make sure there are no signs of infection? Just some things to think about. I know you wanted to be pregnant like yesterday (believe me…we’ve all been there!), but I would suggest maybe just doing the old protocal this month, and seeing what happens. and if they all fail to grow again, then look into the donor sperm. I don’t know that sperm or egg failure can or should be determined from one round of failed IVF…it could have just been a fluke. So I say give it another go. Good Luck!!!


#3

I agree with Kate. When I had my failed IVF my dr said everything went perfect and I was just on the wrong side of the coin toss. I was told that even with IVF it’s still a 50/50 chance of it working, just like any normal pregnancy. My insurance also covers another one and I’m not even second guessing doing it again. I love the idea of using donor sperm as well as your husbands. I’m gonna ask my dr about that when I get ready to do it again this month. Ultimately you have to decide what you are comfortable with. Good luck!!

Michelle


#4

thanks for the feedback :slight_smile: I’m just trying to make an effort to plan out the upcoming year. and not having regular cycles just makes it so difficult. I do not know if I can ovulate on my own, but I don’t THINK I do.
So, I may ask the doctor more questions before I dive right back into the aggressive treatments.

If I had normal cycles, but couldn’t get pregnant that would be one thing. But not having normal cycles is like an extra kick in the pants because I have to try to regulate them, in order to stay sane, AND deal with the challenges that “infertility” brings.

anyways, good luck to you both!