Failed IUIs - want to avoid IVF help


[SIZE=3][FONT=Calibri]Hi all,[/FONT][/SIZE]

[SIZE=3][FONT=Calibri]My fiancée and I have been trying to have a baby for the past 8 months. [/FONT][FONT=Calibri]She was on clomid for the first 3 cycles…she produced 2 mature follicles each cycle. No BFP’s.[/FONT][/SIZE]
[FONT=Calibri][SIZE=3]We then moved to follistim. She has been on follistim for the last 4 cycles. For some reason she isn’t responding very well to it. The first cycle she had 1 mature follicle, the 2nd and 3rdshe had two mature follicles – her dosage ranged from 75-150 during those three cycles (she only started 75 the very first round of follistim). She is now on #4 with follistim, she has been taking 150mg since last Wednesday. She went in for an ultrasound this morning, and our Doctor pretty much told her flat out that she isn’t responding to follistim, she is only going to have one mature follicle this cycle (it’s 16 right now)… If we don’t want to cancel the cycle, he is going to bring her in again tomorrow…trigger her, and on Friday morning imseminate. [/SIZE][/FONT]

[FONT=Calibri][SIZE=3]So… we don’t understand why she isn’t responding to follistim. Especially at 150. All her other levels have been normal, and the doctor said, aside from having a little bit of an ovulation problem there isn’t anything else wrong (that he can see).[/SIZE][/FONT]
[SIZE=3][FONT=Calibri]Now my fiancée is frustrated and exhausted beyond belief…this process is really taking a toll on her (well both of us, but obviously her more). Between doctor visits, medications and sperm we have spent 25K on this so far and we are running out of money. She wants to do IVF, but I don’t think we should jump into that, I’d rather keep trying, but what if something is wrong….we would be wasting our time with IUI. But how successful is IVF? Our insurance wont cover it until she has had 12 unsuccessful IUIs, but we were talking about paying out of pocket somehow. But again, I don’t want her to have to go through IVF… I wish this whole process was easier. Ah I don’t know what to do. Where should we go from here? Is there other medicines she can try??[/FONT][/SIZE]

[FONT=Calibri][SIZE=3]Thanks for any help.[/SIZE][/FONT]


What testing has she had?


I know just what your talking about…

My husband and I have been ttc for 3 years now with no luck we have a wonderful reproductive Specialist clinic. I have went through endless blood tests and Sonohysterogram test and countless Ultrasounds, and everything came back fine well good really. So then my husband had to go have a full Semen Analysis again all came back fine that was all done 14 months ago. I did 10 rounds on 100mg of Clomid again nothing…so they did 3 rounds on 150mg of Clomid with a trigger shot and did an IUI, nothing…then the Dr. wanted us to do another IUI but this time with Follitim, trigger shot and Progesterone gel and again another :bfn: . And were at the same point you seem to be we have spent alot of money and I just want to go to the IVF but at the sametime i’m so scared that it wont work and at this point i’m alittle bit of an emotional mess at this point and my husband wants to take some time away from it all bc it just has us both stressed and thats never good…I will say a :pray: for ya’ll…


Hi Daysable,

I have the same question as prinny. What tests did she have so far? When I went through my IUIs I had a hysterosalpingagram, hysterosonogram and ultrasounds. I also had several panels done for bloodwork. I was on gonal-f which is similar to follistim and my dose was 300units each injection. I ended up with five follicles at one time at the most. All my IUIs were bfn. We moved onto IVF and wished we did it sooner! I got pregnant on my first try and have a 19month daughter now. Not sure how old your fiancee is either however I was 36 and my RE had no doubts of getting me preggo on the first try. Feel free to message me if you have further questions. Good luck to you both!


Hi guys, thanks so much for your responses.
She has had dozens of internal ultrasounds…and she had this test done…I can’t remember the exact name…but it flushed out her fallopian tubes and checked to see if there was any blockages. And all came back good. She does have a cyst measuring 22x24 on her left ovary. Not sure if that has anything to do with our troubles? The doctor said he doesnt think it would. She also took birth control for 17 years to prevent ovarian cysts. She went off of it two months before we started trying.


Hi Daysable,
You mentioned that she was on birth control for 17 years to prevent ovarian cysts. Has she been diagnosed with Polycystic Ovarian Syndrome? My sister had PCOS and was on birth control for it as well. Her doctor ended up putting her on a drug named metformin which she got pregnant on her second cycle after taking the medication.

As far as the cyst she has, I had a cyst that was found during my one IUI and my RE said we were going to skip that month. When I questioned him as to why skip it, apparently a cyst can give off some negative chemical which would possibly jepordize the cycle. So we decided not to waste the money and I went on birth control pill to help get rid of the cyst. The pill worked and then I was off and running for the next month! I do not know if anything I mentioned was talked about with your RE but if not maybe it would be something to bring up to your doctor!

Again, good luck and if you need more info do not hesitate to ask. These boards work wonders with support and information!



I completely understand. My wife had her 7th IUI yesterday and we have yet to have any blip of a positive outcome. Its draining, as you said, especially for her - but for me too.

I don’t have any advice about the follistim because my wife hasn’t used it. She did natural once, then clomid 4 times, and then Bravelle last time and this time (I have no idea what the difference between Bravelle and Follistim is).

I, too, don’t want my wife to do IVF. She’s on the fence, but leaning toward not. We plan to adopt internationally, and would much rather use the money we have saved for that. But again, if we would have known that it wouldn’t work the first 6 times (and likely won’t work again, this 7th time) we would have been better off just starting with IVF as far as costs go! It’s frustrating!

Anyway, our doctor told us that IVF has about a 65% success rate on the first try. But, I’m skeptical it would work for us mainly because they said that there was no reason why IUI wouldn’t work for us, and it hasn’t.

All that to say, I definitely understand where you’re coming from.