Fermara - PCOS - Infertility


Hello ladies, I feel a little alone in my situation so I am writing to see if there are even any similar situations out there.

I was first diagnosed with PCOS and put on 1000mg of Metformin a day. After trying this for two cycles, each cycle being three months my doctor pushed it to 2000mg of Metformin a day. After being on the Metformin and Clomid and having no success I finally went to see a Reproductive Endocrinologist. Once all of my testing was completed he concluded that I no longer needed to be on the Metformin and took me off of it. He then diagnosed me with having 21- Hydroxylase Deficiency. He then tested my husband and he also tested positive for carrying the gene. So now, we have been waiting 4 months to get into a Genetic Counselor before continuing any further. We have still being trying the natural way every month while waiting but no success. After seeing the Genetic Counselor if we still want to proceed, we will be put on Fermara.

My question to you ladies are, do any of you have a similar or the same diagnosis. Have any of you been put on Fermara to help conceive and what have been the outcomes. I feel very lost and alone in this situation because I cannot find any forums online regarding this deficiency. Any help that you ladies can lend would be fantastic!

I need to also mention that I do have a very healthy beautiful 2yr old baby boy. It took us 3 years to conceive him but we just figured it was timing, we didn’t know we actually had fertility issues. So I believe I CAN conceive since I have him, just wondering how likely my chances are at conceiving again.


no advice, but I also have PCOS and my Dr wants me to try Fermara. I haven’t started it yet but best of luck to you! :pray: