[QUOTE=alexi]I am not too familiar with all the terms yet but I supposed empty gestational sac is also known as a blighted ovum? I transferred two CGH normal chromosome blasts. My RE thinks I either have ectopic or a blighted ovum? I told her yesterday I do not understand how normal chromosome blasts end up as a blighted ovum?
She said she doesnt know either. Very comforting indeed. She said we did the steroid, endometrial biopsy, the only thing she could think of doing for next cycle is doing intralipid infusion. How can intralipid infusion prevent your blasts growing into a beautiful gestational sac with yolk sac and fetal pole inside?
We only have two frozen blasts left also CGH normal. To be honest before I see this doctor (I switched to her in January this year), I didnt think we would even get any normal blasts because of my previous history of chemical pregnancies. I cried when she told me we had 6 normal blasts and starting to build up my hope again but now this… It is hard for me to keep my faith that this will ever work after all this.[/QUOTE]
I think your doctor knows why embryos in general can become blighted ovums, but no one can tell why any SPECIFIC embryo might become a blighted ovum. Any number of things could cause a blighted ovum other than chromosomal abnormalities, and almost all of those things you have no control over. This is just my insight, but a blighted ovum could be caused by an egg that is initially missing important organelles or cellular mechanisms, if mitotic cell divisions begin to fail, if conditions in the uterus aren’t nourishing the embryo, if something is wrong with the sperm… It could even be DNA issues other than just aneuploidy, like a freak accident translocation mutation (where the DNA from your mother and father make an exchange, but the “cut” in the DNA happened someplace important). These are just a few of the thousands of unlikely ways things might go wrong, but when you add up all of those unlikely things, then it ends up being a common occurrance for everyone. In your case, if you have a blighted ovum, then its just probably a freak accident.
I’m sorry if I’m not saying any of this gently. I find that when I’m searching for answers from doctors, having them try to “break things to me gently” results in omission of important information.
It’s not over for you yet. It may not be a blighted ovum or an ectopic, but even if it is, you have very good AMH levels, so most embryos you make that end up as 5 day blastocysts are probably in tip-top shape. You mentioned you have 6? I would kill for 6. My wife and I wouldn’t get 6 five day blastocysts if we did 6 cycles, and we’re only 30 years old. IVF was made for people like you. It’s like you’ve got a bicycle in a foot race. Regardless of the outcome, I think you can take solace in your advantages.