I’m sure this topic has been thoroughly discussed but my search though these pages has not pulled up any collective discussion.
I just met with my RE following a failed IVF cycle. Should we decide to do another cycle, he mentioned Human Growth Hormone (HGH) but then quickly said he did feel in my particular case the added cost is justified - based mostly on my age (39). He said they typically recommend/use for women 40+. So my question was what makes 40 vs. 39 so special. Kicking the ball back to me, he said if I wanted to try it, he would agree but again - didn’t believe the added cost was justified at this point. Since it is now my decision I need more data to make an informed one.
So my questions: (1) does anyone know of any recent publications addressing the use of HGH and IVF? The most recent I could find was 2010, and only one. (2) for women that have used HGH as part of their protocol - did you feel it made a significant difference in your results?
If you would like to provide advice, here are my details…This particular cycle resulted in only 3 eggs at max med levels, all of which fertilized abnormally. This is a significant difference from my last cycle (9 eggs - all good and a BFP). Granted my successful cycle was three years ago. In my RE’s defense, he did try to cancel my cycle based off of day 5 E2 levels less than 100 but I asked to push forward because the low (but within average range) amh scared me into thinking I’ll only get a few eggs anyway. Whether or not this was a good decision…don’t know.
My amh and fsh are low and high within the averages for women my age. RE said the abnormal fertilization could have occurred as a result of pulling the eggs too early or egg quality. We’ll never know for sure. My reduced number of eggs could be the result of just an “off” cycle but based on my amh levels it could also be an indication of low reserve. Again, he explained we can’t know for sure.
DH and I decided we can try one more time. Of the three doctor’s at the practice, one recommended we stop based on the probability of success being low and psychological toll of another cycle. We are also considering this as a valid option.
Since I want there to be no regrets, I believe I know the answer to my HGH decision but would still like to have as much information as possible.
Thanks for reading.