Infertility Story


#41

Hi, Roxie1513!
I had an ovarian cyst deliting surgery (2007) and 3 miscarragies. Last month had 5th bfn after IVF+DE and now absolutely devastated, absolutely exhausted. I couldn’t talk to anybody during last few weeks. Only few days ago came back to my job. I thought that I would be able to move to surrogacy if nothingwork out but now, I understand that I need a break. And I am not even sure that I will…
BTC a great clinic buy can’t give me time for thinking it over. I need to decide in a short time if I want to continue. Don’t know what to do…
Sorry, just wanted to support you but bothering you with my failure((
How are you? How is your journey going on? Did you decide to go for surrogacy with btc or some other clinic? Have you already heard about their innovation?


#42

I’m sorry to hear you’re feeling like this…God love you poor thing, He’s got his plan for you.
Look, I’ve shared this on other threads, but thought this might be helpful for you.~
BioTexCom Center for Human Reproduction offers patients who are above 40 and for those, who suffer from low levels of AMH, an innovative program that makes it possible to get pregnant with their own eggs. The donation of mitochondria is an innovation and a breakthrough in the field of ART and the fertility treatment. This program gives women, who underwent numerous unsuccessful IVF cycles, aged 40+, (patients with low mitochondrial functional activity), an excellent chance to give birth to a child who shares a genetic relationship with her and her partner. How is this possible?
Mitochondrion is one of the most important components of any living cell, including the egg. In simple words, mitochondrion is the cell’s energy station. Essentially, its work consists in supplying the cell with vital energy for its normal functioning.
Women that went through multiple unsuccessful IVF attempts, as well as of older reproductive age, need to restore oocyte mitochondria in order to successfully become pregnant. A woman can become pregnant only if there are functionally active mitochondria in her oocytes. Donation of mitochondria will allow thousands of hopeless women to give birth to a healthy child through IVF using mitochondrial donation.
To carry out such a procedure, an egg donor with a high functional activity of mitochondria (a blastocyst production rate of 70% or more), a patient (willing to get pregnant), and sperm for in vitro fertilization are required. Healthy functionally active mitochondria are taken from a donor’s oocyte and integrated with the patient’s cells. Next, fertilization with sperm and transfer of a healthy embryo into the patient’s uterus is performed.
Mitochondria donation is a unique assistive reproductive technology, which is basically the implantation of a healthy and functionally active donor mitochondria into the cells of an infertile patient, that provides the patient’s cell with the necessary energy and contributes to successful pregnancy.
I did google for more info on the point. ad what I read completely differed!! The point is that other clinics offer the similar procedure, BUT they take out the core from the donor’s egg and place it back to the patient’s egg. This cell core has the hugest impact on the future baby’s DNA.
At Bio tex com clinic they transfer mitochondria only! And those do not influence the DNA at all. This means you get genetically related to YOU baby!! even though you use donor’s help.
I hope my message will help you in a way.
Wishing you quick recovery and all the best with your further steps. Hugs.


#43

Thank you for your kind words.
I’ve read somewhere on the internet quite an interesting piece of info concerning blocked Fallopian tubes and their role in fertility. I was shocked how complicated the issue might be! From what I’ve read, Fallopian tubes can be damaged in many different ways. If the furthest end of the tube is blocked, then the tube cannot pick up an ovulated egg. This may also cause the tube to collect fluid and dilate, creating what is known as a hydrosalpinx. It is important to know if your blocked tubes created a hydrosalpinx, because the fluid that collects inside can decrease your chance of successful pregnancy with IVF by about 50%. If your doctor finds a hydrosalpinx, they may recommend that you have the tube removed or blocked using a surgical procedure, so that the fluid from the hydrosalpinx does not communicate with the uterus. Damaged fallopian tubes may sometimes be partially open. This can increase your risk of an ectopic pregnancy, or a pregnancy that implants outside the uterus. The fallopian tube is the most common place for an ectopic pregnancy to grow. An ectopic pregnancies can be dangerous if it grows large enough to cause heavy bleeding, and so in almost all cases it should be removed using surgery or medication.
Ladies often write about their low AMH levels when it comes to fertility. But this issue becomes really not too serious with the innovative method the clinic we’ve been with offers now. - Donation of mitochondria. (I’ve already posted a lot about this method. You may have a look at https://biotexcom.com/a-unique-method-to-get-pregnant-in-your-40s-with-your-own-eggs/ for details). What I wanna say is that there are so many reasons we should take into account when facing fertility issues. Only professionals can help with those!! We had done a lot of research before went to Bio Tex Com for treatments. I don’t regret a thing staying with them. Guys know the field. they invest a lot in continuous researches to improve their treatment plans. Besides everyone can find the package which suits him. Worthy choice!


#44

Hi. As I’ve posted previously, we passed OE surrogacy treatment plan in BioTex, Kiev. And here are some of their really strong sides. They achieve positive results due to day by day improving techniques. Their embryologists work with fresh genetic material (eggs/sperm cryopreservation is used only at patient’s will). Such approach automatically multiplies chances for the successful fertilization. It is known and proven that quality of eggs gets worse during the freezing process leading to the failed IVF attempts. In addition to the spermogram doctors at BioTexconduct sperm analysis for apoptosis. Conducting this medical test embryologist determines presence of the damaged sperm cells which prevent successful conception and can cause child’s DNA damage. In the case of cells’ poor quality, doctor prescribes appropriate medication, afterwards perform reanalysis and successfully fertilize the egg. Karyotype analysis is the part of a standard analyzes set (karyotype test shows the total number of chromosomes, the sex of the person being studied, and if there are any structural abnormalities with any of the individual chromosomes which can cause child’s diseases). Conducting programs of the egg donation and surrogate motherhood doctors calculate the ideal “window of implantation”. This is the most successful period for the embryo transfer without disturbing its structure and endometrium integrity. Starting to work with the infertile couple, their specialists use only individual approach in each case. First of all, members of the medical staff carry out detailed diagnostics of patients in order to identify clearly the seeds of the disease or reasons of the unsuccessful IVF attempts. There are no identical protocols as BioTex team does not work in the traces. Because positive result of any medical program is their main goal! Doctors of the Kiev center walk the line of the latest methods of treatment. So, for example, embryologists use the most successful method of working with blastocysts, namely, embryo transfer on the fifth day. It greatly increases the chance of pregnancy during the in vitro fertilization programs.
I should say that the surrogacy program at BioTex covers all the bases and works in the clients’ favor. Unlike other European clinics, the surrogacy program cost there is significantly lower and service is better than in the high-level medical centers. Depending on diagnosis, doctor can recommend surrogacy program with donor or own eggs. Patients pay for the program on a phased basis: igning the contract. Before the pickup / puncture procedure. When surrogate mother reaches 12th week of pregnancy. As act of delivery starts. During the final stage of the program, when biological parents receive all necessary documents and leave the clinic with the newborn.
Signing the contract, clients receive a complete package of services. In particular, BioTex drivers meet patients at the airport and provide them with a transfer from/to the clinic, hotel, embassy, etc. Clients live in the clinic’s homes, hotels which are regularly visited by pediatrician who specializes in the newborn children. Doctor monitors condition of the newborn’s health, advises parents on all issues they are interested in. In the case of premature birth, BioTex covers all the expenses concerning necessary medications, procedures, and child’s stay in the hospital if it is needed. During the whole period of the program manager and interpreter accompany couple. and organize all processes, coordinate patients, prepare all documents and help clients to go through the program without difficulties. Interpreters who accompany clients are accredited to work in the state institutions, as well as have an experience on working with the documentation for the surrogacy (Ministry of Justice, Ministry of Foreign Affairs). All services listed above are included in the price of the program you choose.


#45

Thank you for your informative answer. Friends of mine underwent surrogacy in Ukraine but before contacting the clinic they did a huge research on the point, considering surrogacy in the UK, US, European countries. First, they looked into the process in the US first. There it was extremelly expensive - $60 – 150k!! For them it was a factor (actually as for everybody else!) Of course things change a lot if you have a family member or friend that is willing to carry it for you. But the process might not be smooth at all. For ex., a surrogate backs out or unfortunate situation like a miscarriage. In this case you automatically have to pay at least $5k to match with another surrogate and do their health workup through the agency! Evidently, there are so many costs that could be added at any time. A surrogate receives on average of $20 – 30k for the pregnancy. The bigger sum of money goes to the agency or lawyer. Also in some states, surrogate mothers retain a parental right to the child, and can even pursue custody. (Even though the embryos placed in the surrogate have both of yourDNA!) The surrogate mother’s name is on the birth certificate. Then a couple has to go through the process of adopting the baby in court. The biggest factor, though, is time. All of the legal paperwork, signing a contract, matching a surrogate, having the surrogate go through the work-up etc. It’s been a year or two since you started the process. Discouraged, they started to look into surrogacy overseas. There were so many options! But some were very sketchy. They read some horror stories about Thailand and India. Both the countries, as a result, have shut down their surrogacy practices not too long ago.
Then how it actually came in favour of Ukraine. The huge factor for them as I’ve mentioned above was process cost. In Ukrainian biotexcom it turned out to be relatively affordable. Clinic’s all-inclusive plans for 32k - 50k euro. They covered absolutely everything outside of your plane tickets. Meds, accommodation, transportation, food. All things that involve IVF, surrogate screening and birth at the hospital. And it was also the same price if donor eggs are chosen to use instead. It was a nice back-up plan to have if things didn’t work out with OE at no additional cost! This blew them away! The best part about it is that they guaranteed them a baby (If the first surrogate doesn’t work out, they will try again with another until they are successful!)
Also Ukraine is one of the few places where the laws favor the intended parents rather than the surrogate. Under Ukrainian law, the baby is yours from the moment of conception. Once the baby is born, they put down your names in the birth certificate. Surrogate can’t claim any rights!! I believe all this makes Ukraine the prefect infertility treatment destination.


#46

Hi lovely ladies here. This is one of the ttc/pregnancy no-no. I believe, binge drinking while ttc does make getting pregnant more difficult. Among other things to avoid – smoking. Cigarette smoke is loaded with chemicals that, if you do smoke, can seriously interfere with your normal functioning, including damaging the genetic material in eggs and sperm. Then excess consumption of caffeine is linked not only to negative pregnancy outcomes, but to impaired fertility as well. Overcaffeination can prevent eggs from maturing properly. Another thing - big weight gains/ weight losses. Keeping your weight within a healthy range is important, but if you need to gain or lose weight, it’s better to do so in a drawn-out, balanced way, as opposed to gaining or losing a lot of weight in a short amount of time. Big swings in weight will inhibit normal hormone functioning, which could throw off your body’s ability to ovulate regularly, or at all. A couple of things more - bigger fish like shark, swordfish, and tilefish, among others, are high in the heavy metal mercury. Mercury can be devastating for a baby’s neurological development in the womb, so you should make sure that any fish you eat before or during pregnancy don’t contain high levels of it. Although it’s very important to get plenty of exercise when you’re trying to conceive or are pregnant, there is definitely a thing as too much. Overexercise or a lack of body fat can disrupt the body’s normal hormonal functioning, resulting in irregular or absent ovulations, so if your workouts are overly intense, you should check with your healthcare provider.


#47

This is what my Dr at Biotexcom explained on the point. I suppose this might be useful to know.
Human reproduction is not very efficient, and there is a lot of wastage in the process. As a result of fertilisation, the single set of 23 chromosomes from the egg combines with the single set of 23 from the sperm to create a zygote . This is still a single cell (the fertilised egg ) BUT now it has 2 sets of chromosomes, or 46 chromosomes). This zygote then divides serially to produce progressively more cells , resulting in an embryo , which continues to develop into a baby if all goes well. And it won’t if there are chromosomal abnormalties.
In ICSI, a single sperm is injected into each egg on an inverted microscope. This technique eliminates the need for the sperm to dissolve a path through the shell of the egg and to bind to the egg membrane. Some sperm do not have these capabilities ( which is why they will not be able to fertilise the egg on their own) . ICSI allows to give these sperm a "piggy back ride "into the egg, to ensure that fertilisation will occur. Over 70% of mature eggs fertilise after ICSI in a good lab. I believe one should consider ICSI is there’s sperm issues. This way is said and proved to be more effective.