My husband’s brother was diagnosed with Y Chromosome Microdeletion. He went through mTESE surgery and he and his wife were hoping to do ICSI with IVF, but unfortunately, the mTESE was unsuccessful. He and his wife have since moved on from infertility procedures and have adopted a child.
As far as we know, my husband did not inherit the micro deletion. We have been fortunate to not have any difficulty having children. Our first child was a girl, so we did not have to consider the deletion. We are expecting a boy this fall and are now beginning to do research about what, if anything, we can do for our son when he is young that could possibly help him if he inherits this condition. We are meeting with a genetic counselor in a few weeks, but the people on this board are so knowledgeable that I thought I would ask a few questions here as well.
-Are there indications that cord blood may be helpful in treating this condition in the future? We did not bank it for our daughter, but we are considering it for our son.
-Would you have your son tested when he is young to see if he inherited the condition?
-Would you have your son freeze sperm when he is a teenager?
-Any other suggestions?
I have read many articles online, but most are not written for the layperson. And it’s unclear to me whether this condition can be passed down if my husband doesn’t appear to have inherited it. (fyi, his father had five children. There is another brother, but he is not in a serious relationship and has chosen not to be tested at this time. My FIL’s brother had all girls, so that family is unaffected.)
We want to make sure that we have done everything we can for our son to allow him to take advantage of future advances in technology. The fact is we will love all of our grandchildren (if we are lucky to have them) regardless of whether they are biological or not. This is about giving our future son options.
Thank you for any help.
P.S. We are not in a position to consult with BIL and SIL to seek their advice for personal reasons.