Very low pregesterone at 21 day cycle check


#1

ok, this is my very first post and I am hoping I can get some insight.
My husband and I have been trying to conceive for about a year and a half. We got pregnant with our first son very easy, actually he is the best surprise ive ever gotten.
My doctor started me on clomid three months ago.
First month-50mg day 3-7
Second month 50mg days 5-9
Third month-100mg days 5-9
On the third month they checked my progesterone level on day 21 of my cycle and it was at 0.7!!! When I do the OPK it kept getting to the second area (fertile area) but never went to the third. On the little cheap ones Ive had for previous months everything went like clockwork. Before trying clomid, my cycle was on time every time same time. Now It alters from 30 days to 31 last month being at 35 which I am sure is the clomid throwing me off.
So now this month my doctor wants to do 150mg of clomid and is hoping it will do the trick. Ive been so hopeful every month but starting to wonder if anything is ever going to work. Especially after finding out how low my levels were last month. Is there anything else I can do or a shot I should ask for?
Thanks for the help everyone and listening to me rant.:bsv:


#2

This is just about the very first question anyone here will ask you, so I’ll go ahead and ask it–are you seeing a reproductive endocrinologist (fertility specialist)? If the OPKs are giving you weird results, and three cycles of Clomid so far haven’t gotten you pregnant, I’d suggest that it’s time to move to one if you haven’t already. The Clomid rounds you’ve been on sound pretty typical, although yes, some of us have also required a trigger shot (a shot of a big dose of hCG, and the brand usually seems to be Ovidrel or Pregnyl). You could ask your doc about that, because it might just be that you have trouble ovulating and that could do the trick. If you are currently with an RE, then I would ask to sit down with him or her and really talk about your previous cycles and where you’d like to go from here. You may be at a point where you want to ask for a full panel of blood work, ultrasounds, and possibly at some point an HSG (hysterosalpingogram) to rule out the various causes of infertility. Hope that helps, and good luck.


#3

Did your doctor just hand you clomid and say take this and baby dance when you get a +opk? Or are you getting ultrasounds to know when your follies are ready? Upping your meds might actually hurt you more than help you. You need to be monitored and triggered to force ovulation when they are ready. You probably were given to much clomid and your body said nope im not ovulating. That progesterone number shows ovulation didn’t even happen. I’d have a talk with my doc before taking an even higher dose of clomid.


#4

My progesterone was 3 or lower on several cycles and I was told it was way too low to have ovulated. The OPKs I was using backed this up. If you know you aren’t ovulating, the answer is not necessarily to take higher and higher doses of Clomid, especially given some it’s nastier side effects. Like the other responses have said, I wouldn’t take a higher dose until I had a conversation with my doctor. If insurance covers it or you can afford it, go consult with an RE. They know way more about this stuff than a regular OB/GYN.

Good luck on your journey!


#5

There are lots of options with the clomid. Here is what we tried and it worked.

I tried one cycle of Clomid 50mg with no success. I then joined an ovulation monitoring program at my doctors office. He didn’t want to increase me to 100mg just yet because we didn’t want to increase chance of multiples. So we did the 50mg again day 5-9 then did an ultrasound. It showed there was some progress but not enough so we did 5 more days on the 50mg. IT DID THE TRICK! Ultrasound showed 2 really good follicles! So I continued to do the ovulation strips for the next 2 days. Still negative so they had me do trigger shot of Ovidrel. With that I got a positive ovulation strip. We did IUI that day. So we are now 1 week into the the 2ww.

Talk to your doctor about doing ultrasound the day after you finish clomid to see how it worked! This way you are not blindly taking the medication and wondering what it is doing.


#6

[QUOTE=boogabear]ok, this is my very first post and I am hoping I can get some insight.
My husband and I have been trying to conceive for about a year and a half. We got pregnant with our first son very easy, actually he is the best surprise ive ever gotten.
My doctor started me on clomid three months ago.
First month-50mg day 3-7
Second month 50mg days 5-9
Third month-100mg days 5-9
On the third month they checked my progesterone level on day 21 of my cycle and it was at 0.7!!! When I do the OPK it kept getting to the second area (fertile area) but never went to the third. On the little cheap ones Ive had for previous months everything went like clockwork. Before trying clomid, my cycle was on time every time same time. Now It alters from 30 days to 31 last month being at 35 which I am sure is the clomid throwing me off.
So now this month my doctor wants to do 150mg of clomid and is hoping it will do the trick. Ive been so hopeful every month but starting to wonder if anything is ever going to work. Especially after finding out how low my levels were last month. Is there anything else I can do or a shot I should ask for?
Thanks for the help everyone and listening to me rant.:bsv:[/QUOTE]

To me it sounds like, currently, you’re not ovulating. If you don’t ovulate your body doesn’t produce a corpus luteum (cyst) and that is what produces the progesterone to sustain a pregnancy.

I also, with DD, used the CBEFM and on 100mg of Clomid got a positive that I was ovulating - once.

I tried 150mg to get a BFP with DS and unfortunately it didn’t work. I hope it works for you!

I would recommend, if you’re not already, adding lots of red raspberry leaf tea daily - I liked to make mine in a big jug like I would make orange juice. I would take several tea bags, hot water and let them steep then I would add a little sugar or honey as sweetener and keep it in the fridge and drink it iced! It was yummy that way!

I’d also eat some brazil nuts or take some selenium to help with uterine lining since Clomid can deplete that.

Clomid can also cause hostile CM so I would definitely recommend some PreSeed lubricant for during DTD. You can even put some in an Instead menstrual cup and put the cup in after BD’ing and that way it keeps all the sperm up near the cervix.

Have you tried Femara? Sometimes people that don’t have luck with Clomid have great luck with it.

You could also add injects to Clomid and add IUI with it to help things along. Any little bit helps! You could also use a trigger shot of HCG to force ovulation. You would probably have to get an U/S to make sure your follie(s) are ready though. Maybe more than one too…

It was actually a combo cycle that got me a BFP twice. One was a blighted ovum, sadly but the second time I overstimmed and had to switch to IVF but it worked!

If your P4 is low and you know you ovulated definitely ask for some progesterone support in the luteal phase. It may mean you have a luteal phase defect and need supplementary progesterone to sustain the pregnancy.

GL and PM me if you have any questions!


#7

I just wanted to chime in here. I too have very low progesterone. I was put on Clomid for this reason. Many people don’t know that Clomid can be used for ovulation OR low progesterone. Anyway, I was put on 50 mg of Clomid, then 100 mgs, then 200 mgs. I got pregnant on the 3 IUI with only 200 mgs of Clomid but lost the baby at week 6 due to low progesterone. I stayed with the 200 mgs of Clomid and 2 IUIs later after the loss got pregnant again but this time I was also on progesterone supplements = vaginal inserts 3 times a day. This pregnancy went on to be fully successful and now we have a healthy 20 month old girl.