Need advice please on what action to take with low ovarian and if I still have a chance in hell in ever seeing one of these:preg: :grr: :grr: :grr:
If you decide that you would like to attempt fertility treatment using your own oocytes despite a lower chance for success, make sure that your doctor is fully onboard with this approach and that you are financially and psychologically able to handle the stress of, perhaps, several failed treatment attempts. Get a second opinion if you have any lingering questions. Be aggressive. Continual pursuit of insemination cycles is costly and such an approach does not address fertilization issues. A properly planned IVF cycle can lead to answers and may help a couple with the closure process. And, there will be some patients who actually take home miracles when given the opportunity for a treatment cycle despite dismal treatment pre-screening test results. A young patient with few oocytes may still have one or two eggs capable of resulting in a live-birth. Ovarian reserve testing identifies patients that have a lower probability of conceiving. Such tests address averages and not individuals. I will personally never forget one patient who at 33 years of age failed her clomid challenge test and several IVF stimulation attempts. She subsequently delivered a term infant by spontaneous conception two years after the delivery of donor egg twins. When making the choice to move on to donor eggs or adoption be sure that you have explored all available treatment options to your satisfaction.
Omg, I’m sorry. Low ovarian reserve is a huge obstacle unless under doc’s supervision. Some might recommend taking viamins and supplements to improve the situation. They are more likely to recommend healthy fertility dieting and doing sports. Yet others trying accupuncture or some other technique. Anyway, you have to get this problem pinned and seek for professional help. See your doc soon on this point. Hoping for you.
Hi, I’m sorry to hear this. The first thing which comes into my mind is opting for donor egg. Not insisting!! But seems the case is tough. We ended up with using DE ourselves. Thought this might be helpful for you.
Medical factors for the recipient.
All recipients, regardless of age should have a complete blood count, blood tests for HIV, hepatitis B and C, cytomegalovirus, rubella, toxoplasmosis and RH factor before starting a donor egg cycle.
Do you have any health problems that would be affected by a pregnancy such as cardiovascular disease? Are you on prescription medication, etc?
If you are over 40 and are considering the donor egg options, make sure that you have a current electrocardiogram, mammogram, glucose tolerance test and chest film.
Have you talked to an obstetrician about the risks relating to pregnancy, labor and delivery for women in your age category?
Have you discussed the risks of multiple births, which is quite high with donor eggs?
Have you asked about the miscarriage rate after embryo transfer?
Has your husband or partner’s semen been tested lately?
Will the clinic use estrogen and progesterone to prepare the endometrium lining of your uterus. Will the clinic require a mock cycle first? Which type of estrogen is used?
This is not the entire list, but it’s aimed to take a good start. I know you want more people here to say - come on, luv, give OE one more try! My suggestion though is, please, do consider the both options well. May god help you.
I’m adding the set of questions on PSYCHOLOGICAL PREPARATION.~
Have you gone for couple counseling to discuss the donor egg option?
Is counseling provided for the donor?
Is counseling provided for the donor’s husband?
Does the donor have children already? Has she discussed ovum donation with her children? If not, has she considered ramifications if later when she wants her own family, infertility is an issue?
Is the donor aware of the need for ovulation induction and associated possible risks/complications?
Is the donor aware that if there are extra embryos they may be frozen for later use?
Is the donor aware that should you decide to, the frozen embryos in storage could be destroyed, donated to research or donated to another couple?
If the donor has a history of breast or ovarian cancer in her family, is she aware of the possible increased risk of developing cancer from using ovulation drugs
Have you decided about an amniocentesis? It may not be necessary if the donor is under 34 years old.
Have you discussed the secrecy or openness issue relative to telling the child? Who, if anyone, will you tell that you are considering or trying this option?
Donor egg path is not so easy though. One should consider a great amount of things!!
Oh, thank you very much. I believe your post might be of huge help to those in the case. My clinic has got a large egg donor pole. No wonder though. It’s the most reputable clinic in the area. All their donors are best screened for all possible diseases. They all are very young - from 18 to 25 yrs old. In perfect mental and physical health. Their families are also studied for the genetic diseases, so that the clinic can make sure they aren’t the carriers of any. All their donors are with proven fertility. meaning they have at least 1 healthy kid on their own. The clinic guarantees at least 3 perfect A grade embies for the transfer. which is another pro. There are 600 donors in the database and it’s growing. So, the choice is never easy. The final word though, the dr in the charge of the program has.
Hi, I’m sorry you’re facing this. My advice is to find a clinic that specialises with people with low AMH. Check out the clinics with stats for women in the older age categories to show you who is good at treating lower AMH levels. Depending on your situation, rarely your testing may include:
Based on your symptoms, your doctor may request a hysteroscopy to look for uterine or fallopian tube disease. During hysteroscopy, your doctor inserts a thin, lighted device through your cervix into your uterus to view any potential abnormalities.
Laparoscopy is minimally invasive surgery involves making a small incision beneath your navel and inserting a thin viewing device to examine your fallopian tubes, ovaries and uterus. A laparoscopy may identify endometriosis, scarring, blockages or irregularities of the fallopian tubes, and problems with the ovaries and uterus.
Genetic testing helps determine whether there’s a genetic defect causing infertility.
Not everyone needs to have all, or even many, of these tests before the cause of infertility is found. You and your doctor will decide which tests you will have and when.
Hope this helps.
I was new to this group. So people had to forgive me when I was not savvy with the website, abbreviations etc. I was 42 years old and that time 6 days past 5 day transfer of a donor egg embryo and felt the need to “talk” to others rather than continue to simply stalk those boards ha. In the last 3 years I’d got pregnant on my own and subsequently had 3 miscarriages (2 conclusively genetic issues, 1 inconclusive and all lost before 8 weeks). I had 3 failed IUIs & IVFs as well before moving straight to donor eggs. I could not take any more disappointment. With all the times I was pregnant I felt no symptoms and so was never even able to be hopeful. I was constantly worrying. So when I was 6dp5dt and I felt nothing and of course was bringing me right back into that negative space. The odd thing was, I had zero symptoms from the estrace and progesterone. so maybe I was just not someone who was very sensitive to that stuff. but I felt like I’m losing hope already. When I said zero symptoms I mean zero. my boobs had not been sore since I started meds. no cramping. no increased urination. I refused to do hpt and run the risk of ruining more of my days. Btw my lining at transfer was 11mm and the embryo was AA grade. I failed again then. I couldn’t hold the pregnancy again. So my dr’s next decision was to turn for the surro’s help.
I’m sorry to hear about your multiple miscarriages. A mc after IVF, or a non-assisted pregnancy, often has no discernible cause. The dreaded word ‘unexplained’ is often used. But that doesn’t mean being healthy isn’t important. At least three months before your treatment, start a health regime. Don’t go mad; but be sensible. Stop smoking – a known cause of miscarriage. Stop drinking alcohol, and definitely avoid non-prescription drugs. Get your BMI in-range and eat a balanced diet, including plenty of fruit and vegetables. Once you’re pregnant, avoid night shifts and heavy lifting. It could make all the difference.Many IVF patients find it hard to remember to take their medication. But it’s vital you do, because a miscarriage is technically possible after just one missed dose. It’s after transfer that complacency really kicks in. Have your medication in your bag and on the kitchen table. And set the alarm on your mobile device. A dose of realism is needed when you’re 42. Miscarriage rates are 50 per cent. Live-birth rates for IVF with your own eggs are only 10 to 15 per cent. And the likelihood of chromosomal abnormalities are higher than average. Donor eggs take on all three. If your objective is a baby, and reduced heartache, donor eggs or donor embryos are a consideration. It’s hard to bid farewell to your own eggs. But we eventually chose donated eggs and succeeded. Our recent 7 wks scan went on well. Things look just great.
Shared this on another thread~~
@@ Center for Human Reproduction offers patients who are above 40 and for those, who suffer from low levels of AMH, an innovative program that makes it possible to get pregnant with their own eggs. The donation of mitochondria is an innovation and a breakthrough in the field of ART and the fertility treatment. This program gives women, who underwent numerous unsuccessful IVF cycles, aged 40+, (patients with low mitochondrial functional activity), an excellent chance to give birth to a child who shares a genetic relationship with her and her partner. Mitochondrion is one of the most important components of any living cell, including the egg. In simple words, mitochondrion is the cell’s energy station. Essentially, its work consists in supplying the cell with vital energy for its normal functioning. Women that went through multiple unsuccessful IVF attempts, as well as of older reproductive age, need to restore oocyte mitochondria in order to successfully become pregnant. A woman can become pregnant only if there are functionally active mitochondria in her oocytes. Donation of mitochondria will allow thousands of hopeless women to give birth to a healthy child through IVF using mitochondrial donation. To carry out such a procedure, an egg donor with a high functional activity of mitochondria (a blastocyst production rate of 70% or more), a patient (willing to get pregnant), and sperm for in vitro fertilization are required. Healthy functionally active mitochondria are taken from a donor’s oocyte and integrated with the patient’s cells. Next, fertilization with sperm and transfer of a healthy embryo into the patient’s uterus is performed. Mitochondria donation is a unique assistive reproductive technology, which is basically the implantation of a healthy and functionally active donor mitochondria into the cells of an infertile patient, that provides the patient’s cell with the necessary energy and contributes to successful pregnancy.
I read a lot about DNA, talked to the doctors about that and they explained that, actually, Mitochondrial DNA and Human DNA are slightly different things. It only gives that necessary energy to the oocyst and helps with developing an embryo and make it stronger. DNA is in the core of the mitochondria, which are not used for donation. Therefore, genetically, mitochondria have no effect on the embryo.
Hope this helps.